:root{--bg:#060612;--bg-card:rgba(14,14,30,0.9);--bg-surface:#0c0c1e;--text:#e2e8f0;--text-muted:#7a7fa0;--accent:#8b5cf6;--accent2:#a78bfa;--gradient:linear-gradient(135deg,#8b5cf6,#06b6d4,#10b981);--border:rgba(255,255,255,0.07);--radius:14px;--font:'Inter',sans-serif;--mono:'JetBrains Mono',monospace;--dna-a:#ef4444;--dna-t:#3b82f6;--dna-g:#10b981;--dna-c:#f59e0b;--rna-u:#e879f9}
[data-theme="light"]{--bg:#f5f0ff;--bg-card:rgba(255,255,255,0.92);--bg-surface:#fff;--text:#1a1a2e;--text-muted:#666;--border:rgba(0,0,0,0.08)}
*{margin:0;padding:0;box-sizing:border-box}
body{font-family:var(--font);background:var(--bg);color:var(--text);min-height:100vh}
.container{max-width:1100px;margin:0 auto;padding:0 1.5rem}
.navbar{position:sticky;top:0;z-index:100;background:rgba(6,6,18,0.85);backdrop-filter:blur(20px);border-bottom:1px solid var(--border);padding:0.75rem 0}
[data-theme="light"] .navbar{background:rgba(245,240,255,0.9)}
.nav-inner{display:flex;align-items:center;justify-content:space-between;gap:1rem}
.brand{text-decoration:none;color:var(--text);font-weight:700;font-size:1.25rem;display:flex;align-items:center;gap:0.5rem}
.brand span{background:var(--gradient);-webkit-background-clip:text;-webkit-text-fill-color:transparent;background-clip:text}
.nav-links{display:flex;gap:0.5rem;align-items:center}
.nav-links a{text-decoration:none;color:var(--text-muted);font-size:0.9rem;padding:0.4rem 0.75rem;border-radius:8px;transition:all 0.2s}
.nav-links a:hover{color:var(--text);background:rgba(139,92,246,0.15)}
.kofi-link{color:#ff5e5b!important;font-weight:600}
.theme-btn{background:none;border:1px solid var(--border);width:36px;height:36px;border-radius:50%;cursor:pointer;font-size:1.1rem;display:flex;align-items:center;justify-content:center;transition:all 0.2s}
.theme-btn:hover{border-color:var(--accent);transform:scale(1.1)}
.hero{text-align:center;padding:2rem 0 1.5rem}
.hero h1{font-size:clamp(1.75rem,4vw,2.75rem);font-weight:800;margin-bottom:0.5rem}
.gradient-text{background:var(--gradient);-webkit-background-clip:text;-webkit-text-fill-color:transparent;background-clip:text}
.hero-sub{color:var(--text-muted);font-size:1rem;max-width:600px;margin:0 auto}
.glass-card{background:var(--bg-card);border:1px solid var(--border);border-radius:var(--radius);padding:1.5rem;margin-bottom:1.5rem;backdrop-filter:blur(10px)}
.glass-card:hover{border-color:rgba(139,92,246,0.2)}
.card-title{font-size:1.2rem;margin-bottom:1rem}
.text-muted{color:var(--text-muted)}.mb-3{margin-bottom:1rem}
.btn{padding:0.6rem 1.2rem;border:none;border-radius:8px;cursor:pointer;font-family:var(--font);font-weight:600;font-size:0.85rem;transition:all 0.2s}
.btn-primary{background:var(--gradient);color:#fff}
.btn-primary:hover{transform:translateY(-2px);box-shadow:0 4px 20px rgba(139,92,246,0.3)}
.btn-secondary{background:transparent;color:var(--text);border:1px solid var(--border)}
.btn-secondary:hover{border-color:var(--accent);color:var(--accent)}
.tool-tabs{display:flex;gap:0.5rem;margin-bottom:1.5rem;flex-wrap:wrap}
.tool-tab{padding:0.7rem 1.2rem;background:var(--bg-card);border:1px solid var(--border);border-radius:10px;color:var(--text-muted);cursor:pointer;font-family:var(--font);font-weight:600;font-size:0.9rem;transition:all 0.2s}
.tool-tab:hover{color:var(--text);border-color:var(--accent)}
.tool-tab.active{background:var(--accent);color:#fff;border-color:var(--accent)}
.panel.hidden{display:none}
.dna-input{width:100%;padding:0.8rem 1rem;background:var(--bg-surface);color:var(--text);border:1px solid var(--border);border-radius:10px;font-family:var(--mono);font-size:1rem;letter-spacing:0.1em;resize:vertical;outline:none;margin-bottom:1rem;text-transform:uppercase}
.dna-input:focus{border-color:var(--accent);box-shadow:0 0 0 3px rgba(139,92,246,0.15)}
.btn-row{display:flex;gap:0.5rem;flex-wrap:wrap}
.results-grid{display:grid;grid-template-columns:repeat(auto-fit,minmax(280px,1fr));gap:1rem;margin-bottom:1.5rem}
.result-card h3{font-size:0.9rem;margin-bottom:0.75rem;color:var(--text-muted)}
.seq-display{font-family:var(--mono);font-size:0.85rem;word-break:break-all;line-height:1.8;padding:0.5rem;background:var(--bg-surface);border-radius:8px;min-height:3rem;max-height:200px;overflow-y:auto}
.seq-display .base{padding:1px 2px;border-radius:3px;margin:0 1px}
.base-A{color:var(--dna-a);background:rgba(239,68,68,0.1)}.base-T{color:var(--dna-t);background:rgba(59,130,246,0.1)}
.base-G{color:var(--dna-g);background:rgba(16,185,129,0.1)}.base-C{color:var(--dna-c);background:rgba(245,158,11,0.1)}
.base-U{color:var(--rna-u);background:rgba(232,121,249,0.1)}
.protein-color .amino{display:inline-block;padding:2px 6px;margin:2px;border-radius:4px;font-weight:600;font-size:0.8rem}
.amino-hydrophobic{background:rgba(239,68,68,0.15);color:#f87171}
.amino-polar{background:rgba(59,130,246,0.15);color:#60a5fa}
.amino-positive{background:rgba(16,185,129,0.15);color:#34d399}
.amino-negative{background:rgba(245,158,11,0.15);color:#fbbf24}
.amino-special{background:rgba(139,92,246,0.15);color:#a78bfa}
.amino-stop{background:rgba(100,100,100,0.2);color:#888}
.stats-grid{display:grid;grid-template-columns:1fr 1fr;gap:0.5rem}
.stat-item{display:flex;justify-content:space-between;padding:0.4rem 0;border-bottom:1px solid var(--border);font-size:0.85rem}
.stat-item .label{color:var(--text-muted)}.stat-item .value{font-family:var(--mono);font-weight:600}
.codon-grid{display:grid;grid-template-columns:repeat(auto-fill,minmax(80px,1fr));gap:6px}
.codon-cell{padding:0.5rem;text-align:center;border-radius:8px;cursor:pointer;transition:all 0.2s;border:1px solid transparent;font-family:var(--mono);font-size:0.8rem}
.codon-cell:hover{transform:scale(1.05);border-color:var(--accent);z-index:1}
.codon-cell .codon-code{font-weight:700;font-size:0.9rem;margin-bottom:2px}
.codon-cell .codon-aa{font-size:0.7rem;color:var(--text-muted)}
.codon-search{margin-bottom:1rem}
.input-modern{width:100%;padding:0.6rem 0.9rem;background:var(--bg-surface);color:var(--text);border:1px solid var(--border);border-radius:8px;font-family:var(--font);font-size:0.9rem;outline:none}
.input-modern:focus{border-color:var(--accent)}
.mutation-controls{display:flex;gap:1rem;align-items:flex-end;flex-wrap:wrap;margin:1rem 0}
.control-group{display:flex;flex-direction:column;gap:0.3rem}
.control-group label{font-size:0.75rem;color:var(--text-muted);text-transform:uppercase}
.control-group select{padding:0.5rem;background:var(--bg-surface);color:var(--text);border:1px solid var(--border);border-radius:8px;font-family:var(--font);outline:none}
.mutation-comparison{margin-top:1rem}
.mutation-comparison .diff-line{font-family:var(--mono);font-size:0.85rem;padding:0.5rem;background:var(--bg-surface);border-radius:8px;margin-bottom:0.5rem;word-break:break-all;line-height:1.8}
.mutation-comparison .diff-line .mutated{background:rgba(239,68,68,0.3);color:#f87171;padding:1px 3px;border-radius:3px;font-weight:700}
#helixCanvas{width:100%;height:200px;display:block;border-radius:8px;background:var(--bg-surface)}
.footer{margin-top:3rem;border-top:1px solid var(--border);padding:2rem 0}
.footer-inner{display:flex;flex-wrap:wrap;gap:2rem;justify-content:space-between}
.footer-brand span{font-weight:700;font-size:1.1rem}.footer-brand p{color:var(--text-muted);font-size:0.85rem;margin-top:0.3rem}
.footer-brand a{color:var(--accent);text-decoration:none}
.copyright{width:100%;text-align:center;color:var(--text-muted);font-size:0.8rem;margin-top:1rem;padding-top:1rem;border-top:1px solid var(--border)}
@media(max-width:768px){.nav-links{display:none}.results-grid{grid-template-columns:1fr}.mutation-controls{flex-direction:column}}